Coconut oil reduces testosterone induced prostate hypertrophy
by Anthony Roberts
Coconut oil is typically avoided by health and wellness mindful consumers because of its high portion of saturated fat. However, a recent research study (*conducted on rodents) provides us great reason to believe that steroid users Camiseta Selección de fútbol de Ecuador should think about adding it to their diets (along with other, less saturated fats, of course). In this study, Sprague-Dawley rats were separated into a number of groups, as well as administered testosterone, either with or without coconut oil (at two different doses, high as well as low). When the animals were sacrificed, the ones who had been provided testosterone with the higher dose of coconut oil, had lower prostate weights in addition to a lower prostate:bodyweight ratio. The researchers speculate that this might be as a result of the significant levels of lauric as well as myristic acid discovered in the fat (which are the exact same acids discovered in saw palmetto, which has likewise been utilized effectively to treat benign prostate growth).
J Pharm Pharmacol. 2007 Jul;59(7):995-9.
Effects of coconut oil on testosterone-induced prostatic hyperplasia in Sprague-Dawley rats.
de Lourdes Arruzazabala M, Molina V, Más R, Carbajal D, Marrero D, González V, Rodríguez E.
Source
Centre of natural Products, national Centre for scientific Research, Cubanacán, Playa, Havana City, Cuba. lourdes.arruzazabala@cnic.edu.au
Abstract
Benign prostatic hyperplasia (BPH) is the benign uncontrolled growth of the prostate gland, leading to problem with urination. Saw palmetto lipid extracts (SPLE), utilized to treat BPH, have been shown to inhibit prostate 5a-reductase, as well as some major components, such as lauric, myristic as well as oleic acids likewise inhibit this enzyme. Coconut oil (CO) is likewise rich in fatty acids, primarily lauric as well as myristic acids. We investigated whether CO avoids testosterone-induced prostate hyperplasia (PH) in Sprague-Dawley rats. animals Camiseta CF Monterrey were distributed into seven groups (10 rats each). A unfavorable control group were injected with soya oil; six groups were injected with testosterone (3 mg kg(-1)) to cause PH: a positive control group, as well as five groups treated orally with SPLE (400 mg kg(-1)), CO or sunflower oil (SO) (400 as well as 800 mg kg(-1)). treatments were provided for 14 days. Rats were weighed before treatment as well as regular thereafter. Rats were then killed as well as the prostates were removed as well as weighed. CO (400 as well as 800 mg kg(-1)), SPLE (400 mg kg(-1)) as well as SO at 800 mg kg(-1), however not at 400 mg kg(-1), considerably decreased the boost in prostate weight (PW) as well as PW:body weight (BW) ratio induced by testosterone (% inhibition 61.5%, 82.0%, 43.8% as well as 28.2%, respectively). because CO as well as SPLE, however not SO, include appreciable concentrations of lauric as well as myristic acids, these results might be attributed to this fact. In conclusion, this research study shows that CO decreased the boost of both PW as Camiseta Sanfrecce Hiroshima well as PW:BW ratio, markers of testosterone-induced PH in rats.
story source